Omimapc

Rustgi(2007)reviewedthegeneticsofhereditarycoloncancer,includingAPC.GeneticHeterogeneityofFamilialAdenomatousPolyposis.Seealsoautosomal ...,TheAPCisanE3ubiquitinligasethattargetscellcycleregulatory...NOTE:OMIMisintendedforuseprimarilybyphysiciansandotherprofessionals ...,WhiletheOMIMdatabaseisopentothepublic,usersseekinginformationaboutapersonalmedicalorgeneticconditionareurgedtoconsultwithaqu...

175100

Rustgi (2007) reviewed the genetics of hereditary colon cancer, including APC. Genetic Heterogeneity of Familial Adenomatous Polyposis. See also autosomal ...

608473 - ANAPHASE

The APC is an E3 ubiquitin ligase that targets cell cycle regulatory ... NOTE: OMIM is intended for use primarily by physicians and other professionals ...

614659

While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified ...

Entry - *607479

The APCDD1 gene encodes a membrane-bound glycoprotein that inhibits Wnt signaling (Shimomura et al., 2010). ▻ Cloning and Expression.

Entry - *611731

The APC gene encodes a multidomain protein that plays a major role in tumor suppression by antagonizing the WNT (see WNT1; 164820) signaling pathway.

SUPPRESSOR APC DOMAIN

While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified ...